The efficacy of amifostine on pathophysiological changes in vasogenic brain edema induced by experimental cold injury model

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چکیده

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The Effect of Amifostine on Pathophysiological Changes in Vasogenic Brain Edema Induced by an Experimental Cold Injury Model Deneysel Soğuk Yaralanma Modeli ile Oluşturulan Vazojenik Beyin Ödeminde Ortaya Çıkan Patofizyolojik Değişiklikler Üzerine Amifostinin Etkisi

AIm: To investigate the effects of amifostine, a cytoprotective agent, on pathophysiological changes in vasogenic brain edema induced by an experimental cold injury model and to compare these changes with dexamethasone. mATErIAl and mEThOds: A total of 138 rats divided into 6 groups. Brain water content (BWC), malondialdehyde (MDA) concentration and myeloperoxidase (MPO) activity in brain tissu...

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ژورنال

عنوان ژورنال: Turkish Neurosurgery

سال: 2014

ISSN: 1019-5149

DOI: 10.5137/1019-5149.jtn.9293-13.0